Origins of science The Greeks used the word episteme for science. Episteme means knowledge, techne (craftsmanship), understanding, and experience. Episteme / science was primarily knowledge from the observation of nature and natural phenomena, which slowly eclipsed the role of the divine and superstition in the organization and understanding of life and the cosmos. In the fifth century BCE, Hippokrates, father of medicine, said there was nothing divine in the disease of epilepsy. Careful observations of the patient and knowledge of the natural origins of diseases sufficed to explain the natural causes of epilepsy. In the fourth century BCE, Aristotle invented biology-zoology. Science shone through his detailed and extraordinary work on the history, classification, anatomy, and behavior of animals. The Arabs called Aristotle The Philosopher. Charles Darwin praised Aristotle to heavens. Aristotle tutored Alexander the Great who conquered the world, making Alexand